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Cyclen lanthanide-based micellar structures for application as luminescent [Eu(iii)] and magnetic [Gd(iii)] resonance imaging (MRI) contrast agents.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2016 Sep 18; Vol. 52 (72), pp. 10858-61. Date of Electronic Publication: 2016 Aug 15. - Publication Year :
- 2016
-
Abstract
- The synthesis of coordinatively unsaturated tetra-substituted 1,4,7,10-tetraazacyclododecane (cyclen) lanthanide complexes is described; these structures, possessing hydrophobic (C12-alkyl) tails and hydrophilic head groups, self-assemble into supramolecular micellar structures in aqueous solution, and hence can be utilised as novel contrast agents for MRI.
- Subjects :
- Cyclams
Europium chemistry
Gadolinium chemistry
Heterocyclic Compounds chemistry
Hydrophobic and Hydrophilic Interactions
Ions chemistry
Contrast Media chemistry
Coordination Complexes chemistry
Lanthanoid Series Elements chemistry
Luminescent Measurements
Magnetic Resonance Imaging
Micelles
Subjects
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 52
- Issue :
- 72
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 27523566
- Full Text :
- https://doi.org/10.1039/c6cc03092k