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Australian Group on Antimicrobial Resistance Australian Enterobacteriaceae Sepsis Outcome Programme annual report, 2014.
- Source :
-
Communicable diseases intelligence quarterly report [Commun Dis Intell Q Rep] 2016 Jun 30; Vol. 40 (2), pp. E229-35. Date of Electronic Publication: 2016 Jun 30. - Publication Year :
- 2016
-
Abstract
- The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2014 survey was the second year to focus on blood stream infections. During 2014, 5,798 Enterobacteriaceae species isolates were tested using commercial automated methods (Vitek 2, BioMérieux; Phoenix, BD) and results were analysed using the Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints (January 2015). Of the key resistances, non-susceptibility to the third-generation cephalosporin, ceftriaxone, was found in 9.0%/9.0% of Escherichia coli (CLSI/EUCAST criteria) and 7.8%/7.8% of Klebsiella pneumoniae, and 8.0%/8.0% K. oxytoca. Non-susceptibility rates to ciprofloxacin were 10.4%/11.6% for E. coli, 5.0%/7.7% for K. pneumoniae, 0.4%/0.4% for K. oxytoca, and 3.5%/6.5% in Enterobacter cloacae. Resistance rates to piperacillin-tazobactam were 3.2%/6.8%, 4.8%/7.2%, 11.1%/11.5%, and 19.0%/24.7% for the same 4 species respectively. Fourteen isolates were shown to harbour a carbapenemase gene, 7 blaIMP-4, 3 blaKPC-2, 3 blaVIM-1, 1 blaNDM-4, and 1 blaOXA-181-lke.
- Subjects :
- Annual Reports as Topic
Australia epidemiology
Bacteremia epidemiology
Bacteremia history
Bacteremia microbiology
Bacterial Proteins genetics
Bacterial Proteins metabolism
Enterobacteriaceae classification
Enterobacteriaceae genetics
Enterobacteriaceae isolation & purification
Enterobacteriaceae Infections history
History, 21st Century
Humans
Microbial Sensitivity Tests
Molecular Typing
Patient Outcome Assessment
Population Surveillance
beta-Lactamases genetics
beta-Lactamases metabolism
Anti-Bacterial Agents pharmacology
Drug Resistance, Bacterial
Enterobacteriaceae drug effects
Enterobacteriaceae Infections epidemiology
Enterobacteriaceae Infections microbiology
Sepsis epidemiology
Sepsis microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1445-4866
- Volume :
- 40
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Communicable diseases intelligence quarterly report
- Publication Type :
- Academic Journal
- Accession number :
- 27522134