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Prognostic Factors of Overall Survival in Upper Urinary Tract Carcinoma: A Systematic Review and Meta-analysis.
- Source :
-
Urology [Urology] 2017 Feb; Vol. 100, pp. 9-15. Date of Electronic Publication: 2016 Aug 08. - Publication Year :
- 2017
-
Abstract
- Several prognostic factors that influence overall survival after radical nephroureterectomy for upper urinary tract urothelial carcinoma have been described. We have performed a systematic review of the literature and meta-analysis. The clinicopathological factors associated with an increased risk of death were age, multifocality, lymphovascular invasion, pT3-4 stage, pT2 vs <pT2 stage, node-positive disease, tumor grade, tumor size, and positive surgical margins. This meta-analysis of published data identified 9 significant predictors of mortality that should be systematically assessed to propose a risk-based strategy for the choice of adjuvant therapy and surveillance after radical nephroureterectomy.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1527-9995
- Volume :
- 100
- Database :
- MEDLINE
- Journal :
- Urology
- Publication Type :
- Academic Journal
- Accession number :
- 27516121
- Full Text :
- https://doi.org/10.1016/j.urology.2016.07.036