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Synthesis and characterization of chitosan/curcumin blends based polyurethanes.
- Source :
-
International journal of biological macromolecules [Int J Biol Macromol] 2016 Nov; Vol. 92, pp. 1074-1081. Date of Electronic Publication: 2016 Aug 03. - Publication Year :
- 2016
-
Abstract
- In this work, new hexamethylene diisocyanate (HMDI) and hyroxylterminated polybutadiene (HTPB) based polyurethanes (PUs) were prepared following step growth polymerization by the introduction of varying mole ratio of chitosan (CH) and curcumin (CUR). Structural study of blends through infrared spectroscopy confirmed the incorporation of CH and CUR into the backbone of the PU. The scanning electron microscopic (SEM) study confirmed the well dispersion of incorporated chitosan/curcumin and homogeneity of surface of synthesized samples. Thermogravimetric analysis (TGA) of PU blends indicated a better thermal stability with 0.25M:0.75M of chitosan to curcumin. Mechanical properties such as modulus and tensile strength of PU blends were found to be better with higher contents of chitosan and curcumin. The same extender composition (1mol BDO, 075mol chitosan and 0.25mol curcumin) based PU showed higher substantial of antimicrobial activity as compared to the all other PUs. On the whole, this work is actually a step towards the generation of novel biocompatible materials preferably useful for biomedical applications.<br /> (Copyright © 2016 Elsevier B.V. All rights reserved.)
- Subjects :
- Bacillus subtilis drug effects
Bacillus subtilis growth & development
Biocompatible Materials pharmacology
Butadienes chemistry
Chitosan pharmacology
Curcumin pharmacology
Disk Diffusion Antimicrobial Tests
Elastic Modulus
Elastomers chemistry
Escherichia coli drug effects
Escherichia coli growth & development
Isocyanates chemistry
Materials Testing
Pasteurella multocida drug effects
Pasteurella multocida growth & development
Polymerization
Polyurethanes pharmacology
Staphylococcus aureus drug effects
Staphylococcus aureus growth & development
Surface Properties
Tensile Strength
Biocompatible Materials chemistry
Chitosan chemistry
Curcumin chemistry
Polyurethanes chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1879-0003
- Volume :
- 92
- Database :
- MEDLINE
- Journal :
- International journal of biological macromolecules
- Publication Type :
- Academic Journal
- Accession number :
- 27497754
- Full Text :
- https://doi.org/10.1016/j.ijbiomac.2016.08.005