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3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
- Source :
-
The Journal of biological chemistry [J Biol Chem] 2016 Aug 05; Vol. 291 (32), pp. 16926. - Publication Year :
- 2016
Details
- Language :
- English
- ISSN :
- 1083-351X
- Volume :
- 291
- Issue :
- 32
- Database :
- MEDLINE
- Journal :
- The Journal of biological chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 27496967
- Full Text :
- https://doi.org/10.1074/jbc.A111.274613