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Who Put the "A" in ATP? Generation of ATP from ADP-Ribose in the Nucleus for Hormone-Dependent Gene Regulation.

Authors :
Ryu KW
Kraus WL
Source :
Molecular cell [Mol Cell] 2016 Aug 04; Vol. 63 (3), pp. 349-51.
Publication Year :
2016

Abstract

In a recent issue of Science, Wright et al. (2016) describe a pathway for the synthesis of nuclear ATP, leading from NAD(+) to poly(ADP-ribose) to ADP-ribose to ATP, which supports the activity of ATP-dependent chromatin remodeling enzymes during hormone-dependent transcription.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1097-4164
Volume :
63
Issue :
3
Database :
MEDLINE
Journal :
Molecular cell
Publication Type :
Academic Journal
Accession number :
27494555
Full Text :
https://doi.org/10.1016/j.molcel.2016.07.018