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Efficacy of scalp hair decontamination following exposure to vapours of sulphur mustard simulants 2-chloroethyl ethyl sulphide and methyl salicylate.
- Source :
-
Chemico-biological interactions [Chem Biol Interact] 2017 Apr 01; Vol. 267, pp. 74-79. Date of Electronic Publication: 2016 Aug 01. - Publication Year :
- 2017
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Abstract
- Chemical warfare agents are an actual threat and victims' decontamination is a main concern when mass exposure occurs. Skin decontamination with current protocols has been widely documented, as well as surface decontamination. However, considering hair ability to trap chemicals in vapour phase, we investigated hair decontamination after exposure to sulphur mustard simulants methyl salicylate and 2-chloroethyl ethyl sulphide. Four decontamination protocols were tested on hair, combining showering and emergency decontamination (use of Fuller's earth or Reactive Skin Decontamination Lotion RSDL <superscript>®</superscript> ). Both simulants were recovered from hair after treatment, but contents were significantly reduced (42-85% content allowance). Showering alone was the least efficient protocol. Concerning 2-chloroethyl ethyl sulphide, protocols did not display significant differences in decontamination efficacy. For MeS, use of emergency decontaminants significantly increased showering efficacy (10-20% rise), underlining their usefulness before thorough decontamination. Our results highlighted the need to extensively decontaminate hair after chemical exposure. Residual amounts after decontamination are challenging, as their release from hair could lead to health issues.<br /> (Copyright © 2016. Published by Elsevier B.V.)
- Subjects :
- Aluminum Compounds pharmacology
Chemical Warfare Agents analysis
Gas Chromatography-Mass Spectrometry
Hair chemistry
Hair pathology
Magnesium Compounds pharmacology
Mustard Gas analysis
Mustard Gas toxicity
Salicylates analysis
Silicates pharmacology
Skin Cream pharmacology
Chemical Warfare Agents toxicity
Decontamination methods
Gases chemistry
Hair drug effects
Mustard Gas analogs & derivatives
Salicylates toxicity
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7786
- Volume :
- 267
- Database :
- MEDLINE
- Journal :
- Chemico-biological interactions
- Publication Type :
- Academic Journal
- Accession number :
- 27492218
- Full Text :
- https://doi.org/10.1016/j.cbi.2016.07.018