Mutations induce conformational changes in folliculin C-terminal domain: possible cause of loss of guanine exchange factor activity and Birt-Hogg-Dubé syndrome.

Authors :: Verma S
Tyagi C
Goyal S
Pandey B
Jamal S
Singh A
Grover A
Source :: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2017 May; Vol. 35 (7), pp. 1568-1573. Date of Electronic Publication: 2016 Aug 02.
Publication Year :: 2017

Subjects :: Birt-Hogg-Dube Syndrome pathology
Guanine chemistry
Guanine metabolism
Humans
Molecular Dynamics Simulation
Mutation genetics
Proto-Oncogene Proteins genetics
Tumor Suppressor Proteins genetics
Birt-Hogg-Dube Syndrome genetics
Protein Conformation
Proto-Oncogene Proteins chemistry
Tumor Suppressor Proteins chemistry

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