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[Genetic variants of the complement components and HLA-antigens associated in patients with psoriasis vulgaris in Japanese].
- Source :
-
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology [Nihon Hifuka Gakkai Zasshi] 1989 Jan; Vol. 99 (1), pp. 77-81. - Publication Year :
- 1989
-
Abstract
- Genetic polymorphisms of the serum complement components (C2, C4, C6, and C7) and HLA-antigens were studied in Japanese patients with psoriasis vulgaris. Among these complement components, positive associations with C4A4 and C4B2 were obtained. In addition to the previously reported haplotypes HLA-Cw6-B13 and Cw6-Bw57-DR7, the extended haplotype HLA-Cw11-Bw46-C4A4. 4B2-BFS-C2C-DRw8 may be a high risk haplotype in Japanese patients with psoriasis vulgaris.
Details
- Language :
- Japanese
- ISSN :
- 0021-499X
- Volume :
- 99
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 2746964