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High-Throughput Microfluidic Device for Circulating Tumor Cell Isolation from Whole Blood.
- Source :
-
Micro total analysis systems : proceedings of the ... [Mu] TAS International Conference on Miniaturized Chemical and Biochemical Analysis Systems. [Mu] TAS (Conference) [Micro Total Anal Syst] 2015 Oct; Vol. 2015, pp. 413-415. - Publication Year :
- 2015
-
Abstract
- Circulating tumor cells (CTCs) are promising markers to determine cancer patient prognosis and track disease response to therapy. We present a multi-stage microfluidic device we have developed that utilizes inertial and Dean drag forces for isolating CTCs from whole blood. We demonstrate a 94.2% ± 2.1% recovery of cancer cells with our device when screening whole blood spiked with MCF-7 GFP cells.
Details
- Language :
- English
- ISSN :
- 1556-5890
- Volume :
- 2015
- Database :
- MEDLINE
- Journal :
- Micro total analysis systems : proceedings of the ... [Mu] TAS International Conference on Miniaturized Chemical and Biochemical Analysis Systems. [Mu] TAS (Conference)
- Publication Type :
- Academic Journal
- Accession number :
- 27453707