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Two New Secondary Metabolites from the Endophytic Fungus Endomelanconiopsis endophytica.
- Source :
-
Molecules (Basel, Switzerland) [Molecules] 2016 Jul 20; Vol. 21 (7). Date of Electronic Publication: 2016 Jul 20. - Publication Year :
- 2016
-
Abstract
- Two new secondary metabolites, endomeketals A-B (1-2), a new natural product (3), and a known compound (4) were isolated from the ethyl acetate extract of the endophytic fungus Endomelanconiopsis endophytica A326 derived from Ficus hirta. Their structures were determined on the basis of extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities against SF-268, MCF-7, NCI-H460, and HepG-2 tumor cell lines. However, no compound showed cytotoxic activity against these human tumor cell lines.
- Subjects :
- Antineoplastic Agents chemistry
Antineoplastic Agents pharmacology
Ascomycota metabolism
Biological Products pharmacology
Cell Line, Tumor
Cell Survival drug effects
Endophytes
Humans
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Structure
Secondary Metabolism
Ascomycota chemistry
Biological Products chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1420-3049
- Volume :
- 21
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Molecules (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 27447605
- Full Text :
- https://doi.org/10.3390/molecules21070943