Back to Search
Start Over
PI(4,5)P2 and L-type Ca(2+) Channels Partner Up to Fine-Tune Ca(2+) Dynamics in β Cells.
- Source :
-
Cell chemical biology [Cell Chem Biol] 2016 Jul 21; Vol. 23 (7), pp. 753-755. - Publication Year :
- 2016
-
Abstract
- The PI(4,5)P2 level in the plasma membrane is dynamically regulated by cytoplasmic ATP production and receptor-mediated transmembrane signaling cascades. In this issue of Cell Chemical Biology, Xie et al. (2016) use optogenetics to micro-manipulate membrane PI(4,5)P2 and reveal how acute PI(4,5)P2 changes can alter intracellular Ca(2+) dynamics and insulin secretion in pancreatic β cells.<br /> (Copyright © 2016 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 2451-9448
- Volume :
- 23
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Cell chemical biology
- Publication Type :
- Academic Journal
- Accession number :
- 27447044
- Full Text :
- https://doi.org/10.1016/j.chembiol.2016.07.001