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Recovery of benthiocarb-inhibited AChE in fish brain: an in vitro study.
- Source :
-
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 1989 Jun; Vol. 17 (3), pp. 317-22. - Publication Year :
- 1989
-
Abstract
- The effects in vivo and in vitro of benthiocarb, an organocarbamate, on acetylcholinesterase (AChE) activity and its recovery in vitro in the brain of the freshwater fish Sarotherodon mossambicus have been studied. Findings revealed that the specific activity of AChE was inhibited both in vivo and in vitro in a concentration-dependent manner. Of the different modulators tested, dexamethasone (0.72 mg), prednisolone (0.74 mg), testosterone (0.9 mg), and ADP (9.5 mg) were found to neutralize the inhibitory effect (IC50 = 0.30 microM) of benthiocarb on AChE.
Details
- Language :
- English
- ISSN :
- 0147-6513
- Volume :
- 17
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Ecotoxicology and environmental safety
- Publication Type :
- Academic Journal
- Accession number :
- 2743920
- Full Text :
- https://doi.org/10.1016/0147-6513(89)90052-3