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[Expert recommendations: Hepatitis C and transplantation].

Authors :
Zimmermann T
Beckebaum S
Berg C
Berg T
Braun F
Eurich D
Herzer K
Neumann U
Rupp C
Sterneck M
Strassburg C
Welker MW
Zachoval R
Gotthardt DN
Weigand K
Schmidt H
Wedemeyer H
Galle PR
Zeuzem S
Sarrazin C
Source :
Zeitschrift fur Gastroenterologie [Z Gastroenterol] 2016 Jul; Vol. 54 (7), pp. 665-84. Date of Electronic Publication: 2016 Jul 18.
Publication Year :
2016

Abstract

With the approval of new direct acting antiviral agents (DAA), therapeutic options for patients with chronic hepatitis C virus (HCV) infection are now generally available before and after liver transplantation (LT). Interferon-free DAA regimens are highly effective therapies and provide a good safety profile. However, the body of clinical evidence in this patient population is limited and the best treatment strategies for patients on the waiting list with (de)compensated cirrhosis and after LT are not well defined. The following recommendations for antiviral therapy in the context of LT are based on the currently available literature and clinical experience of experts in the field, and have been discussed in an expert meeting. The aim of this article is to guide clinicians in the decision making when treating patients before and after LT with DAAs.<br /> (© Georg Thieme Verlag KG Stuttgart · New York.)

Details

Language :
German
ISSN :
1439-7803
Volume :
54
Issue :
7
Database :
MEDLINE
Journal :
Zeitschrift fur Gastroenterologie
Publication Type :
Academic Journal
Accession number :
27429106
Full Text :
https://doi.org/10.1055/s-0042-107360