Back to Search
Start Over
Influence of parity and sexual history on cytomegalovirus seroprevalence among women aged 20-49 years in the USA.
- Source :
-
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2016 Oct; Vol. 135 (1), pp. 82-5. Date of Electronic Publication: 2016 Jun 29. - Publication Year :
- 2016
-
Abstract
- Objective: To assess the influence of parity, as a proxy for exposure to children, and sexual history on cytomegalovirus (CMV) seroprevalence.<br />Methods: Data were retrospectively analyzed from women aged 20-49 years who were tested for CMV immunoglobulin G antibodies in the 1999-2004 National Health and Nutrition Examination Survey, a nationally representative survey of the US population. Logistic regression was used to determine independent variables associated with CMV seroprevalence.<br />Results: Among 3710 women, the age-adjusted CMV seroprevalence was 61.3% (95% CI 58.9%-63.6%). In age-adjusted univariate analysis, women who had given birth at least once had higher overall CMV seroprevalence (66.0%, 95% CI 63.1%-68.9%) than did those who had not given birth (49.0%, 95% CI 44.4%-53.7%; P<0.001). In multivariate logistic analysis, higher CMV seroprevalence was independently associated with number of live births (each additional birth: adjusted odds ratio [aOR] 1.2, 95% CI 1.1-1.3), age at first sexual intercourse (<18 vs ≥18years: aOR 1.3, 95% CI 1.1-1.6), lifetime sexual partners (≥10 vs <10: aOR 1.4, 95% CI 1.1-1.9), and herpes type 2 seropositivity (aOR 1.9, 95% CI 1.5-2.6) after controlling for age, race/Hispanic origin, place of birth, poverty index, and education.<br />Conclusion: Among US women of reproductive age, parity and sexual exposures were independently associated with increased CMV seroprevalence.<br /> (Published by Elsevier Ireland Ltd.)
- Subjects :
- Adult
Age Distribution
Cytomegalovirus
Cytomegalovirus Infections blood
Female
Humans
Logistic Models
Middle Aged
Nutrition Surveys
Odds Ratio
Pregnancy
Retrospective Studies
Risk Factors
Seroepidemiologic Studies
Sexual Behavior
United States epidemiology
Young Adult
Antibodies, Viral blood
Cytomegalovirus Infections epidemiology
Parity
Subjects
Details
- Language :
- English
- ISSN :
- 1879-3479
- Volume :
- 135
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
- Publication Type :
- Academic Journal
- Accession number :
- 27401134
- Full Text :
- https://doi.org/10.1016/j.ijgo.2016.03.032