Aerobic Decomposition of Trialkylquercetins: Structure Characterization and Antiproliferative Effect.

The aerobic decomposition of 3,4',7-O-trialkylquercetins was first reported in this paper. The structures of four new decomposed products were characterized by analyzing the 1D and 2D NMR data, as well as their high resolution mass spectroscopic data. Their antiproliferative activity toward human prostate cancer cells has been assessed through WST-l cell proliferation assay. The decomposition mechanism was also proposed.