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Ebola Virus Epidemiology and Evolution in Nigeria.
- Source :
-
The Journal of infectious diseases [J Infect Dis] 2016 Oct 15; Vol. 214 (suppl 3), pp. S102-S109. Date of Electronic Publication: 2016 Jul 04. - Publication Year :
- 2016
-
Abstract
- Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.<br /> (© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.)
- Subjects :
- Adult
Biological Evolution
Ebolavirus isolation & purification
Female
Hemorrhagic Fever, Ebola transmission
Hemorrhagic Fever, Ebola virology
Humans
Liberia
Male
Middle Aged
Nigeria epidemiology
Phylogeny
Sequence Analysis, DNA
Disease Outbreaks
Ebolavirus genetics
Genome, Viral genetics
Hemorrhagic Fever, Ebola epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1537-6613
- Volume :
- 214
- Issue :
- suppl 3
- Database :
- MEDLINE
- Journal :
- The Journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 27377746
- Full Text :
- https://doi.org/10.1093/infdis/jiw190