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Ebola Virus Epidemiology and Evolution in Nigeria.

Authors :
Folarin OA
Ehichioya D
Schaffner SF
Winnicki SM
Wohl S
Eromon P
West KL
Gladden-Young A
Oyejide NE
Matranga CB
Deme AB
James A
Tomkins-Tinch C
Onyewurunwa K
Ladner JT
Palacios G
Nosamiefan I
Andersen KG
Omilabu S
Park DJ
Yozwiak NL
Nasidi A
Garry RF
Tomori O
Sabeti PC
Happi CT
Source :
The Journal of infectious diseases [J Infect Dis] 2016 Oct 15; Vol. 214 (suppl 3), pp. S102-S109. Date of Electronic Publication: 2016 Jul 04.
Publication Year :
2016

Abstract

Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.<br /> (© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.)

Details

Language :
English
ISSN :
1537-6613
Volume :
214
Issue :
suppl 3
Database :
MEDLINE
Journal :
The Journal of infectious diseases
Publication Type :
Academic Journal
Accession number :
27377746
Full Text :
https://doi.org/10.1093/infdis/jiw190