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Predictive performance of quick Sepsis-related Organ Failure Assessment for mortality and ICU admission in patients with infection at the ED.
- Source :
-
The American journal of emergency medicine [Am J Emerg Med] 2016 Sep; Vol. 34 (9), pp. 1788-93. Date of Electronic Publication: 2016 Jun 07. - Publication Year :
- 2016
-
Abstract
- Objective: The objectives of this study are to investigate the performance of the quick Sepsis-related Organ Failure Assessment (qSOFA) in predicting mortality and intensive care unit (ICU) admission in patients with clinically diagnosed infection and to compare its performance with that of Mortality in Emergency Department Sepsis (MEDS), Acute Physiology and Chronic Health Evaluation (APACHE) II, and Sepsis-related Organ Failure Assessment (SOFA).<br />Methods: From July to December 2015, we retrospectively analyzed 477 patients clinically diagnosed with infection in the emergency department. We compared the performance of SOFA, MEDS, APACHE II, and qSOFA in predicting ICU admission and 28-day mortality.<br />Results: All scores were higher in nonsurvivors and ICU patients than in survivors and non-ICU patients (P< .001). The area under the receiver operating characteristic curve of qSOFA was lower than that of MEDS (0.666 vs 0.751; P< .05) and similar to that of SOFA (0.729) and APACHE II (0.732) in predicting 28-day mortality. The areas under the receiver operating characteristic curve of qSOFA, SOFA, MEDS, and APACHE II in predicting ICU admission were 0.636, 0.682, 0.661, and 0.640, respectively. There were no significant differences among the score systems. In patients with qSOFA scores less than 2 and greater than or equal to 2, 28-day mortality rates were 17.4% and 42.9% (P< .001), and ICU admission rates were 16.0% and 33.3% (P< .001).<br />Conclusions: Quick SOFA predicted ICU admission with similar performance to that of SOFA, MEDS, and APACHE II. Its prognostic ability was similar to that of SOFA and APACHE II but slightly inferior to that of MEDS.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- APACHE
Aged
Aged, 80 and over
Databases, Factual
Female
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Mortality
Organ Dysfunction Scores
Prognosis
ROC Curve
Retrospective Studies
Risk Assessment
Severity of Illness Index
Skin Diseases, Infectious mortality
Central Nervous System Infections mortality
Emergency Service, Hospital
Intensive Care Units statistics & numerical data
Intraabdominal Infections mortality
Pneumonia mortality
Pyelonephritis mortality
Sepsis mortality
Soft Tissue Infections mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1532-8171
- Volume :
- 34
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- The American journal of emergency medicine
- Publication Type :
- Academic Journal
- Accession number :
- 27321936
- Full Text :
- https://doi.org/10.1016/j.ajem.2016.06.015