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[EXPERIMENTAL POSTTERIOIDEKTOMIC FATTY LIVER DISEASE IN RATS].
- Source :
-
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology [Eksp Klin Gastroenterol] 2016 (2), pp. 35-9. - Publication Year :
- 2016
-
Abstract
- Unlabelled: The aim was to investigate the morphological features of the liver in animals at different periods of post-operative hypothyroidism to reproduce the experimental fatty liver disease.<br />Materials and Methods: thyroidectomy was performed 20 laboratory rats, females breed nonlinear, thyroid was mobilized without thyroid thyroidectomy to 10 individuals. The morphological pattern of the rat's liver was studied in terms of 4 and 8 weeks after surgery at the light optical level.<br />Results: 4 weeks after thyroidectomy was found in rat liver protein and fatty degeneration with focal of inflammatory infiltration, against the backdrop of a serous edema. On the 8th week of the experiment observed the progression of degenerative, necroinflammatory processes expressed hydropic dystrophy, atomizing steatosis and the appearance of periportal fibrosis.
Details
- Language :
- Russian
- ISSN :
- 1682-8658
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 27301115