Back to Search Start Over

[EXPERIMENTAL POSTTERIOIDEKTOMIC FATTY LIVER DISEASE IN RATS].

Authors :
Dzhulay GS
Shchelochenkov SV
Petrova MB
Bibikova AA
Source :
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology [Eksp Klin Gastroenterol] 2016 (2), pp. 35-9.
Publication Year :
2016

Abstract

Unlabelled: The aim was to investigate the morphological features of the liver in animals at different periods of post-operative hypothyroidism to reproduce the experimental fatty liver disease.<br />Materials and Methods: thyroidectomy was performed 20 laboratory rats, females breed nonlinear, thyroid was mobilized without thyroid thyroidectomy to 10 individuals. The morphological pattern of the rat's liver was studied in terms of 4 and 8 weeks after surgery at the light optical level.<br />Results: 4 weeks after thyroidectomy was found in rat liver protein and fatty degeneration with focal of inflammatory infiltration, against the backdrop of a serous edema. On the 8th week of the experiment observed the progression of degenerative, necroinflammatory processes expressed hydropic dystrophy, atomizing steatosis and the appearance of periportal fibrosis.

Details

Language :
Russian
ISSN :
1682-8658
Issue :
2
Database :
MEDLINE
Journal :
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology
Publication Type :
Academic Journal
Accession number :
27301115