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Serologic evidence of exposure to influenza D virus among persons with occupational contact with cattle.
- Source :
-
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology [J Clin Virol] 2016 Aug; Vol. 81, pp. 31-3. Date of Electronic Publication: 2016 May 31. - Publication Year :
- 2016
-
Abstract
- Background: Influenza D virus (IDV), a novel influenza virus with proposed classification: family Orthomyxoviridae, genus Influenzavirus D, species Influenza D virus, has been associated with influenza-like illness in cattle and swine. More recently, anti-IDV antibodies have also been detected in small ruminants. A seroprevalence of approximately 1.3% has been estimated for the general human population.<br />Objectives: To gain insights on the zoonotic potential of IDV to human adults with occupational exposure to cattle in north central Florida.<br />Study: A cross-sectional serological study was performed on human serum samples from 35 cattle-exposed and 11 non-cattle-exposed adults to screen for IDV antibodies using hemagglutination inhibition (HI) and microneutralization (MN) assays.<br />Results: A seroprevalence of 91% was detected via HI assay, and 97% by MN assay among individuals working with cattle in Florida. Among non-cattle-exposed individuals, seropositivity determined via MN assay (only) was lower (18%).<br />Conclusions: IDV poses a zoonotic risk to cattle-exposed workers, based on detection of high seroprevalence (94-97%). Whereas it is still unknown whether IDV causes disease in humans, our studies indicate that the virus may be an emerging pathogen among cattle-workers.<br /> (Copyright © 2016 Elsevier B.V. All rights reserved.)
- Subjects :
- Adolescent
Adult
Aged
Agriculture
Animals
Antibodies, Viral blood
Cattle
Female
Florida epidemiology
Hemagglutination Inhibition Tests
Humans
Male
Middle Aged
Occupational Exposure
Orthomyxoviridae Infections
Young Adult
Influenza, Human epidemiology
Influenza, Human immunology
Influenza, Human transmission
Influenza, Human virology
Thogotovirus immunology
Zoonoses
Subjects
Details
- Language :
- English
- ISSN :
- 1873-5967
- Volume :
- 81
- Database :
- MEDLINE
- Journal :
- Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
- Publication Type :
- Academic Journal
- Accession number :
- 27294672
- Full Text :
- https://doi.org/10.1016/j.jcv.2016.05.017