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Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria.

Authors :
Chen X
Wu B
Jayawardana KW
Hao N
Jayawardena HS
Langer R
Jaklenec A
Yan M
Source :
Advanced healthcare materials [Adv Healthc Mater] 2016 Aug; Vol. 5 (16), pp. 2007-12. Date of Electronic Publication: 2016 Jun 10.
Publication Year :
2016

Abstract

A multivalent trehalose-grafted poly(lactic acid) is synthesized and encapsulated with iron oxide magnetic nanoparticles. The magnetic micelles interact with Mycobacterium smegmatis to form orange clusters. Very little particle interaction is found on Staphylococcus epidermidis 35984 or Escherichia coli ORN 208. The presented new approach to the detection of mycobacteria does not require molecular biology reagents or sophisticated instruments.<br /> (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
2192-2659
Volume :
5
Issue :
16
Database :
MEDLINE
Journal :
Advanced healthcare materials
Publication Type :
Academic Journal
Accession number :
27283385
Full Text :
https://doi.org/10.1002/adhm.201600071