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Risk Factors for Cataracts Treated Surgically in Postmenopausal Women.
- Source :
-
Ophthalmology [Ophthalmology] 2016 Aug; Vol. 123 (8), pp. 1704-1710. Date of Electronic Publication: 2016 Jun 07. - Publication Year :
- 2016
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Abstract
- Purpose: To identify risk factors for cataracts treated surgically in postmenopausal women.<br />Design: Population-based, prospective cohort study.<br />Participants: A total of 1 312 051 postmenopausal women in the UK Million Women Study, aged 56 years on average (standard deviation [SD], 4.8), without previous cataract surgery, hospital admission with cataracts, or cancer at baseline, were followed for cataracts treated surgically.<br />Methods: Cox regression was used to calculate adjusted relative risks (RRs) for cataract surgery by lifestyle factors, treatment for diabetes, reproductive history, and use of hormonal therapies.<br />Main Outcome Measures: Cataract surgery identified by linkage to central National Health Service (NHS) records for inpatient and day-patient admissions (Hospital Episode Statistics for England and Scottish Morbidity Records in Scotland).<br />Results: Overall, 89 343 women underwent cataract surgery during an average of 11 (SD, 3) years of follow-up. Women with diabetes were at greatest risk (diabetes vs. no diabetes RR, 2.90; 95% confidence interval [CI], 2.82-2.97). Other factors associated with an increased risk of cataract surgery were current smoking (current smokers of ≥15 cigarettes/day vs. never smokers RR, 1.26; 95% CI, 1.23-1.30) and obesity (body mass index [BMI] ≥30 vs. <25 kg/m(2); RR, 1.12; 95% CI, 1.10-1.14).<br />Conclusions: Diabetes, smoking, and obesity were risk factors for cataract surgery. Alcohol use, physical activity, reproductive history, and use of hormonal therapies had little, if any, association with cataract surgery risk.<br /> (Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Alcohol Drinking adverse effects
Cohort Studies
Contraceptives, Oral, Hormonal administration & dosage
Diabetes Mellitus epidemiology
Female
Humans
Incidence
Middle Aged
National Health Programs
Obesity epidemiology
Prospective Studies
Reproductive History
Risk Assessment
Risk Factors
Smoking adverse effects
Surveys and Questionnaires
United Kingdom epidemiology
Cataract epidemiology
Cataract Extraction statistics & numerical data
Postmenopause
Subjects
Details
- Language :
- English
- ISSN :
- 1549-4713
- Volume :
- 123
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 27282285
- Full Text :
- https://doi.org/10.1016/j.ophtha.2016.04.037