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Early marijuana initiation: The link between prenatal marijuana exposure, early childhood behavior, and negative adult roles.
- Source :
-
Neurotoxicology and teratology [Neurotoxicol Teratol] 2016 Nov - Dec; Vol. 58, pp. 40-45. Date of Electronic Publication: 2016 Jun 01. - Publication Year :
- 2016
-
Abstract
- We investigated the associations among gestational factors including prenatal marijuana exposure (PME), child behavior at age 3, early age of onset of marijuana use (EAOM, <15years), and adult roles at 22years. Participants were drawn from the Maternal Health Practices and Child Development (MHPCD) Project, a longitudinal study of prenatal substance exposure in offspring who have been studied for over 22years since the prenatal phase. Data from the prenatal, birth, 3-, and 22-year phases (N=608) were used in the present study. Age of onset of offspring substance use was determined based on data from the 14-, 16-, and 22-year phases. The subjects were of lower socioeconomic status, 43% were Caucasian and the remaining were African-American, and 48% were males. Early childhood behavior was significantly (p<0.05) related to EAOM after controlling for PME, birth and childhood environmental risk factors, and Conduct Disorder. EAOM was significantly associated with negative adult roles including increased risk of being arrested (p<0.001), lower educational attainment (p<0.001), having a child without being married (p<0.05), and unemployment at 22years (p<0.001). The correlations between PME and negative adult roles and between early childhood behavior and negative adult roles were also statistically significant. Pathway analysis demonstrated that EAOM significantly mediated the associations between PME and fulfillment of adult roles and between early childhood behavior and adult roles. There are a number of intervention points that could be targeted that would have a long-term impact on lowering the probability of EAOM and less success in adult roles.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- Adolescent
Adult
Child
Child, Preschool
Conduct Disorder epidemiology
Female
Humans
Infant
Infant, Newborn
Marijuana Smoking adverse effects
Pregnancy
Prenatal Exposure Delayed Effects psychology
Problem Behavior
Socioeconomic Factors
Young Adult
Cannabis adverse effects
Child Behavior drug effects
Marijuana Smoking epidemiology
Prenatal Exposure Delayed Effects epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1872-9738
- Volume :
- 58
- Database :
- MEDLINE
- Journal :
- Neurotoxicology and teratology
- Publication Type :
- Academic Journal
- Accession number :
- 27263091
- Full Text :
- https://doi.org/10.1016/j.ntt.2016.05.011