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[Acidosis without marked hyperglycemia : Euglycemic diabetic ketoacidosis associated with SGLT2-Inhibitors].

Authors :
Valek R
Von der Mark J
Source :
Medizinische Klinik, Intensivmedizin und Notfallmedizin [Med Klin Intensivmed Notfmed] 2017 Mar; Vol. 112 (2), pp. 145-148. Date of Electronic Publication: 2016 May 24.
Publication Year :
2017

Abstract

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are new antidiabetic drugs that regulate blood glucose levels by increasing urinary glucose excretion. In May 2015, the U.S. Food and Drug Administration (FDA) issued a warning that SGLT2 inhibitors may lead to ketoacidosis. In this report, we describe a case of life-threatening euglycemic ketoacidosis associated with SGLT2 inhibition and evaluate possible mechanisms and triggers.

Details

Language :
German
ISSN :
2193-6226
Volume :
112
Issue :
2
Database :
MEDLINE
Journal :
Medizinische Klinik, Intensivmedizin und Notfallmedizin
Publication Type :
Academic Journal
Accession number :
27221094
Full Text :
https://doi.org/10.1007/s00063-016-0153-0