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[Intraoperative BCNU Wafer Implantation for High-Grade Glioma--A Questionnaire Targeting Japanese Neurosurgeons].

Authors :
Ishikawa E
Yamamoto T
Source :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2016 May; Vol. 43 (5), pp. 603-7.
Publication Year :
2016

Abstract

Carmustine (BCNU) wafer implantation has been used in Japanese patients after resection of high-grade glioma (HGG) since 2013. Wafer implantation plays an important role in improving the prognosis of HGG patients, but it often causes particular changes as observed on neuroimaging and various adverse effects (AEs). Here, we conducted a questionnaire-based survey of Japanese neurosurgeons to determine how they feel about this treatment based on their actual observations. Most neurosurgeons had a positive impression of the treatment based on previous evidence of clinical effectiveness. Additionally, we found that the Japanese neurosurgeons are taking measures to cope with some AEs including cerebral edema, postoperative convulsions, cerebrospinal fluid leakage, and protracted wound healing.

Details

Language :
Japanese
ISSN :
0385-0684
Volume :
43
Issue :
5
Database :
MEDLINE
Journal :
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Type :
Academic Journal
Accession number :
27210091