Quinine unbound concentration is the best marker for therapeutic drug monitoring.

Authors :: de Pablos-Martinez C
Porte L
Fraissinet F
Berry A
Séraissol P
Lavit M
Chatelut E
Concordet D
Gandia P
Source :: Therapie [Therapie] 2016 Oct; Vol. 71 (5), pp. 487-489. Date of Electronic Publication: 2016 Apr 11.
Publication Year :: 2016
Abstract: Quinine monitoring should be based on unbound concentration due to variable unbound fraction in malaria patients.<br /> (Copyright © 2016 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.)

Subjects :: Antimalarials blood
Area Under Curve
Humans
Protein Binding
Quinine blood
Antimalarials pharmacokinetics
Drug Monitoring
Malaria drug therapy
Quinine pharmacokinetics

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