Back to Search
Start Over
NSAID-induced pyloric stenosis leading to oesophageal intramucosal dissection.
- Source :
-
BMJ case reports [BMJ Case Rep] 2016 May 19; Vol. 2016. Date of Electronic Publication: 2016 May 19. - Publication Year :
- 2016
-
Abstract
- We describe a rare case of a 75-year-old woman with significant non-steroidal anti-inflammatory drug (NSAID) use who presented with haematemesis. Upper endoscopy revealed a large (9 cm) intramucosal dissection of the oesophagus without extension into the gastro-oesophageal junction and a severely narrowed pylorus. We postulate that she developed pyloric stenosis due to peptic ulcer disease from chronic NSAID use. This then led to gastro-oesophageal reflux. Undigested pills in the refluxate had contacted oesophageal mucosa, leading to pill-induced oesophageal injury. This, along with vomiting, is postulated to have led to the oesophageal intramucosal dissection. She improved with conservative medical management with a clear liquid diet and proton pump inhibitors, and a follow-up upper endoscopy 1 week later showed recovery of the previously seen intramucosal dissection.<br /> (2016 BMJ Publishing Group Ltd.)
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 2016
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 27199442
- Full Text :
- https://doi.org/10.1136/bcr-2016-215777