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Application of diffusion kurtosis imaging to odontogenic lesions: Analysis of the cystic component.
- Source :
-
Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2016 Dec; Vol. 44 (6), pp. 1565-1571. Date of Electronic Publication: 2016 May 17. - Publication Year :
- 2016
-
Abstract
- Purpose: To assess the feasibility of applying diffusion kurtosis imaging (DKI) to common odontogenic lesions and to compare its diagnostic ability versus that of the apparent diffusion coefficient (ADC) for differentiating keratocystic odontogenic tumors (KCOTs) from odontogenic cysts.<br />Materials and Methods: Altogether, 35 odontogenic lesions were studied: 24 odontogenic cysts, six KCOTs, and five ameloblastomas. The diffusion coefficient (D) and excessive kurtosis (K) were obtained from diffusion-weighted images at b-values of 0, 500, 1000, and 1500 s/mm <superscript>2</superscript> on 3T magnetic resonance imaging (MRI). The combination of D and K values showing the maximum density of the probable density function was estimated. The ADC was obtained (0 and 1000 s/mm <superscript>2</superscript> ). Values for odontogenic cysts, KCOTs, and ameloblastomas were compared. Multivariate logistic regression modeling was performed to assess the combination of D and K model versus ADC for differentiating KCOTs from odontogenic cysts.<br />Results: The mean D and ADC were significantly higher for ameloblastomas than for odontogenic cysts or KCOTs (P < 0.05). The mean K was significantly lower for ameloblastomas than for odontogenic cysts or KCOTs (P < 0.05). The mean values of all parameters for odontogenic cysts and KCOTs showed no significant differences (Pā=ā0.369 for ADC, 0.133 for D, and 0.874 for K). The accuracy of the combination of D and K model (76.7%) was superior to that of ADC (66.7%).<br />Conclusion: Use of DKI may be feasible for common odontogenic lesions. A combination of DKI parameters can be expected to increase the accuracy of its diagnostic ability compared with ADC. J. Magn. Reson. Imaging 2016;44:1565-1571.<br /> (© 2016 International Society for Magnetic Resonance in Medicine.)
- Subjects :
- Adolescent
Adult
Aged
Child
Diagnosis, Differential
Feasibility Studies
Female
Humans
Male
Middle Aged
Observer Variation
Odontogenic Cysts pathology
Odontogenic Tumors pathology
Radiography, Dental methods
Reproducibility of Results
Sensitivity and Specificity
Young Adult
Diffusion Magnetic Resonance Imaging methods
Image Enhancement methods
Image Interpretation, Computer-Assisted methods
Odontogenic Cysts diagnostic imaging
Odontogenic Tumors diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1522-2586
- Volume :
- 44
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of magnetic resonance imaging : JMRI
- Publication Type :
- Academic Journal
- Accession number :
- 27185307
- Full Text :
- https://doi.org/10.1002/jmri.25307