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Neutrophil-to-Lymphocyte Ratio Increases in Patients With Dry Eye.
- Source :
-
Cornea [Cornea] 2016 Jul; Vol. 35 (7), pp. 983-6. - Publication Year :
- 2016
-
Abstract
- Purpose: To assess the neutrophil-to-lymphocyte ratio (NLR) as an indicator of inflammation in patients with non-Sjögren dry eye disease.<br />Methods: Serum NLR and C-reactive protein values were determined in 33 patients with dry eye and in 32 controls. The NLR was calculated by dividing the neutrophil count by the lymphocyte count.<br />Results: Characteristics of the dry eye and control groups were similar. The mean NLR value was 2.8 ± 1.4 (range: 1.1-6.1) in the dry eye group and 1.6 ± 0.7 (range: 0.8-2.8) in the control group (P = 0.002, t test). The mean C-reactive protein value was 0.6 ± 0.7 mg/dL (range: 0-2.3 mg/dL) in the dry eye group and 0.5 ± 0.6 mg/dL (range: 0-1.9 mg/dL) in the control group (P = 0.307, t test).<br />Conclusions: The NLR values were found to be higher in patients with non-Sjögren dry eye than in controls. This result suggests that non-Sjögren dry eye disease may be associated with systemic inflammation or the NLR values may increase in local inflammatory ocular diseases.
Details
- Language :
- English
- ISSN :
- 1536-4798
- Volume :
- 35
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Cornea
- Publication Type :
- Academic Journal
- Accession number :
- 27158804
- Full Text :
- https://doi.org/10.1097/ICO.0000000000000872