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Pharmacotherapy for Dementia: A Practical Approach to the Use of Cholinesterase Inhibitors and Memantine.
- Source :
-
Drugs & aging [Drugs Aging] 2016 Jul; Vol. 33 (7), pp. 451-60. - Publication Year :
- 2016
-
Abstract
- Cholinesterase inhibitors and memantine are the only classes of drugs approved for the treatment of dementia due to Alzheimer's disease. This article provides evidence-based recommendations to address the issues regarding the use of cholinesterase inhibitors and memantine in clinical practice. It includes their efficacy, timing, assessment, use in institutionalized patients, combined use, and use in other dementia types. However, most of the studies are of short duration (<1 year) and are mainly focused on cognitive and global improvement, whereas the practical issue of their use in daily practice such as optimal duration of treatment, long-term efficacy and delaying institutionalization are limited.
- Subjects :
- Alzheimer Disease drug therapy
Cholinesterase Inhibitors administration & dosage
Cholinesterase Inhibitors adverse effects
Humans
Memantine administration & dosage
Memantine adverse effects
Cholinesterase Inhibitors therapeutic use
Dementia drug therapy
Memantine therapeutic use
Practice Guidelines as Topic
Subjects
Details
- Language :
- English
- ISSN :
- 1179-1969
- Volume :
- 33
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Drugs & aging
- Publication Type :
- Academic Journal
- Accession number :
- 27154396
- Full Text :
- https://doi.org/10.1007/s40266-016-0372-3