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iPSCs Offer a New Look at GATA1-Trisomy 21 Cooperation.
- Source :
-
Cell stem cell [Cell Stem Cell] 2016 May 05; Vol. 18 (5), pp. 563-4. - Publication Year :
- 2016
-
Abstract
- GATA1 mutations and trisomy 21 are inextricably linked in the neonatal leukemia of children with Down syndrome (DS). A recent report by Banno et al. (2016) sheds new light on the mechanism of the synergy between these genetic alterations by modeling hematopoietic abnormalities with patient-derived induced pluripotent stem cells.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1875-9777
- Volume :
- 18
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cell stem cell
- Publication Type :
- Academic Journal
- Accession number :
- 27152438
- Full Text :
- https://doi.org/10.1016/j.stem.2016.04.007