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Synthesis and Antiviral Bioassay of New Diphenyl Ether-based Compounds.
- Source :
-
Chemical biology & drug design [Chem Biol Drug Des] 2016 Oct; Vol. 88 (4), pp. 511-8. Date of Electronic Publication: 2016 May 27. - Publication Year :
- 2016
-
Abstract
- A set of diphenyl ether derivatives bearing different heterocycles were synthesized from 4-phenoxybenzohydrazide 1 in good yield. Synthesized compounds were screened against a broad panel of viruses in different cell cultures and some of the synthesized compounds showed promising antiviral properties.<br /> (© 2016 John Wiley & Sons A/S.)
- Subjects :
- Antiviral Agents chemical synthesis
Antiviral Agents chemistry
Antiviral Agents pharmacology
Biological Assay
Biphenyl Compounds chemistry
Cells, Cultured
Drug Evaluation, Preclinical
Ether chemistry
Humans
Models, Molecular
Molecular Structure
Pyrazoles chemistry
Pyrazoles pharmacology
Pyridines chemistry
Pyridines pharmacology
Biphenyl Compounds chemical synthesis
Biphenyl Compounds pharmacology
Ether chemical synthesis
Ether pharmacology
Viruses drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1747-0285
- Volume :
- 88
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Chemical biology & drug design
- Publication Type :
- Academic Journal
- Accession number :
- 27096302
- Full Text :
- https://doi.org/10.1111/cbdd.12775