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Recent refinements to cranial implants for rhesus macaques (Macaca mulatta).
- Source :
-
Lab animal [Lab Anim (NY)] 2016 May; Vol. 45 (5), pp. 180-6. - Publication Year :
- 2016
-
Abstract
- The advent of cranial implants revolutionized primate neurophysiological research because they allow researchers to stably record neural activity from monkeys during active behavior. Cranial implants have improved over the years since their introduction, but chronic implants still increase the risk for medical complications including bacterial contamination and resultant infection, chronic inflammation, bone and tissue loss and complications related to the use of dental acrylic. These complications can lead to implant failure and early termination of study protocols. In an effort to reduce complications, we describe several refinements that have helped us improve cranial implants and the wellbeing of implanted primates.
- Subjects :
- Acrylic Resins adverse effects
Animals
Craniotomy adverse effects
Dental Cements adverse effects
Implants, Experimental microbiology
Magnetic Resonance Imaging
Monkey Diseases microbiology
Monkey Diseases prevention & control
Neurophysiology instrumentation
Neurophysiology methods
Postoperative Complications veterinary
Surgical Wound Infection microbiology
Surgical Wound Infection prevention & control
Surgical Wound Infection veterinary
Wound Healing
Implants, Experimental adverse effects
Macaca mulatta surgery
Skull surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1548-4475
- Volume :
- 45
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Lab animal
- Publication Type :
- Academic Journal
- Accession number :
- 27096188
- Full Text :
- https://doi.org/10.1038/laban.997