Synchronous intramolecular cycloadditions of the polyene macrolactam polyketide heronamide C.

Authors :: Booth TJ
Alt S
Capon RJ
Wilkinson B
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2016 May 11; Vol. 52 (38), pp. 6383-6. Date of Electronic Publication: 2016 Apr 19.
Publication Year :: 2016
Abstract: A growing number of natural products appear to arise from biosynthetic pathways that involve pericyclic reactions. We show here that for the heronamides this can occur via two spontaneous pathways involving alternative thermal or photochemical intramolecular cycloadditions.

Subjects :: Molecular Conformation
Photochemical Processes
Streptomyces chemistry
Cycloaddition Reaction
Lactams, Macrocyclic chemical synthesis
Lactams, Macrocyclic chemistry

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