Back to Search
Start Over
Effect of sleeve gastrectomy bariatric surgery-induced weight loss on serum AMH levels in reproductive aged women.
- Source :
-
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2016 Oct; Vol. 32 (10), pp. 799-802. Date of Electronic Publication: 2016 Apr 17. - Publication Year :
- 2016
-
Abstract
- Objective: This study aims to evaluate the change in serum anti-Mullerian hormone (AMH) levels in patients with morbid obesity undergoing bariatric surgery for weight loss.<br />Material and Methods: In this prospective observational study, 75 patients of reproductive age (20-35 years) undergoing bariatric surgery for morbid obesity were followed up after six months to determine the changes in weight, Body Mass Index (BMI), menstrual pattern and serum AMH. The results were further studied on basis of pre operative classification of patients in polycystic ovary syndrome (PCOS) and non-PCOS group.<br />Result: The serum AMH levels were statistically higher in patients of PCOS group pre operatively and at the end of six months in comparison to non-PCOS patients. The AMH values reduced post operatively in both groups significantly so much in the values though not significant statistically. Non-PCOS patients had lower AMH values pre operatively and showed a trend towards reducing ovarian reserve after six months. The overall change in AMH values in both groups was statistically significant as was the normalization of menstrual irregularity.<br />Conclusion: Morbidly obese patients with PCOS appear to benefit from bariatric surgery both in terms of regularization of menstrual function and normalization of serum AMH values.
- Subjects :
- Adult
Female
Humans
Treatment Outcome
Young Adult
Anti-Mullerian Hormone blood
Bariatric Surgery methods
Gastrectomy methods
Menstruation Disturbances blood
Menstruation Disturbances etiology
Obesity, Morbid blood
Obesity, Morbid complications
Obesity, Morbid surgery
Polycystic Ovary Syndrome blood
Polycystic Ovary Syndrome complications
Weight Loss physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1473-0766
- Volume :
- 32
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
- Publication Type :
- Academic Journal
- Accession number :
- 27087540
- Full Text :
- https://doi.org/10.3109/09513590.2016.1169267