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Efficacy and Safety of Minoxidil 5% Foam in Combination With a Botanical Hair Solution in Men With Androgenic Alopecia.
- Source :
-
Journal of drugs in dermatology : JDD [J Drugs Dermatol] 2016 Apr; Vol. 15 (4), pp. 406-12. - Publication Year :
- 2016
-
Abstract
- Androgenic alopecia (AGA) is the most common type of hair loss in men, characterized by hair miniaturization, hairline recession, and vertex balding. It affects approximately 50% of men, negatively affecting self-esteem and sociability. Topical minoxidil formulations are approved up to a 5% concentration for men, but patient adherence to treatment is challenged by gradual results that may be perceived as a lack of initial benefit. Herbal extracts, which are also believed to promote healthier-looking hair, have a long history of use in hair care formulations. The safety and efficacy of a twice-daily regimen of 5% minoxidil foam used in combination with a novel botanical hair solution was evaluated in a 12-week, multicenter, single-arm, open label study in 56 subjects with mild to moderate AGA. Assessments included investigator ratings of improvement and subject self-ratings of satisfaction. Investigator ratings indicated significant improvement in scalp hair coverage and perception of overall treatment benefit in as early as 4 weeks (P<.001). Subject self-ratings were significant for improved hair growth and hair appearance in as few as 4 weeks (P<.05). The regimen was well tolerated, and subjects indicated a high degree of satisfaction. Investigator and subject-assessed efficacy and subject satisfaction with this novel regimen provide clinicians with an effective treatment option for AGA that also provides a high level of patient satisfaction, which may help promote patient adherence to long-term treatment.
- Subjects :
- Administration, Topical
Adult
Drug Compounding
Drug Therapy, Combination
Hair Preparations chemistry
Humans
Male
Middle Aged
Minoxidil chemistry
Pharmaceutical Solutions administration & dosage
Pharmaceutical Solutions chemistry
Plant Extracts chemistry
Treatment Outcome
Young Adult
Alopecia diagnosis
Alopecia drug therapy
Hair Preparations administration & dosage
Minoxidil administration & dosage
Patient Satisfaction
Plant Extracts administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1545-9616
- Volume :
- 15
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of drugs in dermatology : JDD
- Publication Type :
- Academic Journal
- Accession number :
- 27050695