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Dietary Lipid and Carbohydrate Interactions: Implications on Lipid and Glucose Absorption, Transport in Gilthead Sea Bream (Sparus aurata) Juveniles.
- Source :
-
Lipids [Lipids] 2016 Jun; Vol. 51 (6), pp. 743-55. Date of Electronic Publication: 2016 Mar 29. - Publication Year :
- 2016
-
Abstract
- A digestibility trial was performed with gilthead sea bream juveniles (IBW = 72 g) fed four diets differing in lipid source (fish oil, FO; or a blend of vegetable oil, VO) and starch content (0 %, CH-; or 20 %, CH+) to evaluate the potential interactive effects between carbohydrates and VO on the processes involved in digestion, absorption and transport of lipids and glucose. In fish fed VO diets a decrease in lipid digestibility and in cholesterol (C), High Density Lipoprotein(HDL)-C and Low Density Lipoprotein (LDL)-C (only in CH+ group) were recorded. Contrarily, dietary starch induced postprandial hyperglycemia and time related alterations on serum triacylglycerol (TAG), phospholipid (PL) and C concentrations. Fish fed a CH+ diet presented lower serum TAG than CH- group at 6 h post-feeding, and the reverse was observed at 12 h post-feeding for TAG and PL. Lower serum C and PL at 6 h post-feeding were recorded only in VOCH+ group. No differences between groups were observed in hepatic and intestinal transcript levels of proteins involved in lipid transport and hydrolysis (FABP, DGAT, GPAT, MTP, LPL, LCAT). Lower transcript levels of proteins related to lipid transport (ApoB, ApoA1, FABP2) were observed in the intestine of fish fed the CH+ diet, but remained unchanged in the liver. Overall, transcriptional mechanisms involved in lipid transport and absorption were not linked to changes in lipid serum and digestibility. Dietary starch affected lipid absorption and transport, probably due to a delay in lipid absorption. This study suggests that a combination of dietary VO and starch may negatively affect cholesterol absorption and transport.
- Subjects :
- Animals
Cholesterol metabolism
Cholesterol, HDL metabolism
Cholesterol, LDL metabolism
Dietary Carbohydrates adverse effects
Dietary Fats administration & dosage
Dietary Fats adverse effects
Digestion drug effects
Gene Expression Regulation drug effects
Intestinal Absorption drug effects
Lipid Metabolism drug effects
Plant Oils adverse effects
Starch adverse effects
Dietary Carbohydrates administration & dosage
Genetic Markers drug effects
Glucose metabolism
Plant Oils administration & dosage
Sea Bream physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1558-9307
- Volume :
- 51
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Lipids
- Publication Type :
- Academic Journal
- Accession number :
- 27023202
- Full Text :
- https://doi.org/10.1007/s11745-016-4140-2