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A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates.

Authors :
Haas J
Schätzle MA
Husain SM
Schulz-Fincke J
Jung M
Hummel W
Müller M
Lüdeke S
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2016 Apr 14; Vol. 52 (29), pp. 5198-201. Date of Electronic Publication: 2016 Mar 21.
Publication Year :
2016

Abstract

Spontaneous electron transport to molecular oxygen led to regeneration of oxidised nicotinamide cofactor in cell lysates that contain an alcohol dehydrogenase, a quinone reductase and a quinone mediator. This concept allows the efficient oxidation of alcohols in the presence of alcohol dehydrogenase-containing E. coli lysates and catalytic amounts of the quinone lawsone.

Details

Language :
English
ISSN :
1364-548X
Volume :
52
Issue :
29
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
26998531
Full Text :
https://doi.org/10.1039/c5cc10316a