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Taking forward the World TB Day 2016 theme 'Unite to End Tuberculosis' for the WHO Africa Region.
- Source :
-
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2016 May; Vol. 46, pp. 34-7. Date of Electronic Publication: 2016 Mar 08. - Publication Year :
- 2016
-
Abstract
- Tuberculosis (TB) remains a global emergency, with an estimated 9.6 million new TB cases worldwide reported in 2014. Twenty-eight percent of these cases were in the World Health Organization (WHO) Africa Region, where the annual case detection rate was 281 per 100000 population-more than double the global average of 133 per 100000. Of the 9.6 million people who developed TB, an estimated 1.2 million (12%) were HIV-positive, and the Africa Region accounted for 74% of these cases. Three million people with TB remain undiagnosed and untreated. Globally, an estimated 480000 had multidrug-resistant TB (MDR-TB). Whilst of the African countries, only South Africa has reported a high prevalence of MDR-TB, it is likely that all of Sub-Saharan Africa has an unreported high load of drug-resistant TB. Tragically, in 2014, only 48% of individuals diagnosed with MDR-TB had successful treatment and an estimated 190000 people died of MDR-TB. Of the global TB funding gap of US$ 0.8 billion, the largest funding gap was in the Africa Region, amounting to US$ 0.4 billion in 2015. The MDR-TB pandemic in particular now threatens to devastate entire regions and may fundamentally alter the life-expectancy and demographic profile of many countries in Sub-Saharan Africa. The theme designated for this year's World TB Day, March 24, 2016, is 'Unite to End TB'. From the Africa Region, there is an urgent need to seriously address the political, economic, and social factors that influence host-Mycobacterium tuberculosis interactions and result in disease. Recent political and funder initiatives that provide renewed hope for the alleviation of Africa's TB and TB/HIV problems are discussed.<br /> (Copyright © 2016. Published by Elsevier Ltd.)
- Subjects :
- Africa epidemiology
Disease Eradication
HIV Seropositivity
Humans
Prevalence
Tuberculosis prevention & control
Tuberculosis, Multidrug-Resistant epidemiology
Tuberculosis, Multidrug-Resistant prevention & control
World Health Organization
Antitubercular Agents therapeutic use
Global Health
Mycobacterium tuberculosis drug effects
Tuberculosis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-3511
- Volume :
- 46
- Database :
- MEDLINE
- Journal :
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 26969406
- Full Text :
- https://doi.org/10.1016/j.ijid.2016.03.003