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Invasive urothelial carcinoma, lymphoma-like/plasmacytoid variant, successfully treated by radical cystectomy with adjuvant chemotherapy: a case report.
- Source :
-
Journal of medical case reports [J Med Case Rep] 2016 Mar 08; Vol. 10, pp. 48. Date of Electronic Publication: 2016 Mar 08. - Publication Year :
- 2016
-
Abstract
- Background: Invasive urothelial carcinoma, lymphoma-like/plasmacytoid variant, is a rare histological type of bladder cancer similar to plasma cells and is an aggressive variant of urothelial carcinoma associated with a poor prognosis.<br />Case Presentation: A 41-year-old Asian man was referred to our hospital due to macroscopic hematuria. Cystoscopy detected a non-papillary tumor, and a transurethral resection of the bladder tumor revealed pT1N0M0 bladder cancer. A pathological examination showed high-grade invasive urothelial carcinoma and a component of signet ring cell carcinoma. A follow-up of the transurethral resection with radical cystectomy was carried out, and a pathological examination showed infiltrating urothelial carcinoma, with partial features of the plasmacytoid variant. We added chemotherapy treatment with gemcitabine and cisplatin for two cycles. Our patient has been free from recurrence for 2 years.<br />Conclusions: We herein report the case of a patient with a plasmacytoid variant of urothelial carcinoma controlled with radial cystectomy and subsequent chemotherapy.
- Subjects :
- Adult
Chemotherapy, Adjuvant
Cisplatin administration & dosage
Cystectomy
Deoxycytidine administration & dosage
Deoxycytidine analogs & derivatives
Humans
Male
Neoplasm Invasiveness
Gemcitabine
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Carcinoma, Transitional Cell pathology
Carcinoma, Transitional Cell therapy
Urinary Bladder Neoplasms pathology
Urinary Bladder Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1752-1947
- Volume :
- 10
- Database :
- MEDLINE
- Journal :
- Journal of medical case reports
- Publication Type :
- Academic Journal
- Accession number :
- 26951070
- Full Text :
- https://doi.org/10.1186/s13256-016-0806-x