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Effects of aerobic dance training on blood pressure in individuals with uncontrolled hypertension on two antihypertensive drugs: a randomized clinical trial.
- Source :
-
Journal of the American Society of Hypertension : JASH [J Am Soc Hypertens] 2016 Apr; Vol. 10 (4), pp. 336-45. Date of Electronic Publication: 2016 Feb 12. - Publication Year :
- 2016
-
Abstract
- There is a dearth of reports on possible additive blood pressure (BP)-reducing effect of aerobic exercise on antihypertensive drug in humans. This study investigated the additive BP-reducing effect of aerobic exercise on BP in individuals with uncontrolled hypertension. In this 12-week double-blind study, 120 new-diagnosed individuals with mild-to-moderate hypertension were randomized to receive coamilozide + 5/10 mg of amlodipine + aerobic dance or coamilozide + 5/10 mg of amlodipine alone. Forty-five and 43 participants in exercise and control groups, respectively, completed the 12-week intervention. Addition of aerobic exercise to antihypertensive drug therapy significantly reduced systolic BP (7.1 mm Hg [95% confidence interval: 5.0, 9.3]; P < .001) and diastolic BP (1.7 mm Hg [95% confidence interval: 0.4, 3.0]; P = .009) at 12 weeks. BP control rate differed significantly between exercise (53.9%) and control (35.3%) groups, P < .001. Postintervention, proportion of participants in exercise group who had their number of antihypertensive drug reduced to one (20.3%) differed from that in control group (11.1%); (χ(2) = 11.0; P = .001). Combination of aerobic dance and antihypertensive drugs reduces number of antihypertensive drugs needed to achieve BP control and enhances BP control in individuals with hypertension on two antihypertensive drugs.<br /> (Copyright © 2016 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Aged
Amiloride administration & dosage
Amlodipine administration & dosage
Antihypertensive Agents administration & dosage
Blood Pressure Determination instrumentation
Blood Pressure Determination methods
Combined Modality Therapy
Double-Blind Method
Drug Combinations
Female
Humans
Hydrochlorothiazide administration & dosage
Hypertension drug therapy
Male
Middle Aged
Treatment Outcome
Amiloride therapeutic use
Amlodipine therapeutic use
Antihypertensive Agents therapeutic use
Dance Therapy
Exercise
Hydrochlorothiazide therapeutic use
Hypertension therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1878-7436
- Volume :
- 10
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of the American Society of Hypertension : JASH
- Publication Type :
- Academic Journal
- Accession number :
- 26948962
- Full Text :
- https://doi.org/10.1016/j.jash.2016.02.002