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The Experimental Research (In Vitro) of Carrageenans and Fucoidans to Decrease Activity of Hantavirus.
- Source :
-
Food and environmental virology [Food Environ Virol] 2016 Jun; Vol. 8 (2), pp. 120-4. Date of Electronic Publication: 2016 Mar 04. - Publication Year :
- 2016
-
Abstract
- The effect of carrageenans and fucoidans on the activity of Hantavirus is studied. It has been found that among carrageenans a significant antiviral effect is exerted by the ι-type, which decreases the viral titer by 2.5 log focus forming units per mL; among fucoidans, by a preparation from Laminaria cichorioides, which reduces the number of infected cells from 27.0 to 5.3 after pretreatment of both the macrophage culture and Hantavirus. The antiviral effect of fucoidan from Laminaria japonica is shown to grow in direct proportion to the increase of dose of the preparation.
- Subjects :
- Carrageenan isolation & purification
Orthohantavirus physiology
Plant Extracts isolation & purification
Polysaccharides isolation & purification
Seaweed chemistry
Carrageenan pharmacology
Orthohantavirus drug effects
Laminaria chemistry
Plant Extracts pharmacology
Polysaccharides pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1867-0342
- Volume :
- 8
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Food and environmental virology
- Publication Type :
- Academic Journal
- Accession number :
- 26943130
- Full Text :
- https://doi.org/10.1007/s12560-016-9233-9