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Review of gestational diabetes mellitus effects on vascular structure and function.
- Source :
-
Diabetes & vascular disease research [Diab Vasc Dis Res] 2016 May; Vol. 13 (3), pp. 170-82. Date of Electronic Publication: 2016 Mar 03. - Publication Year :
- 2016
-
Abstract
- Vascular dysfunction has been described in women with a history of gestational diabetes mellitus. Furthermore, previous gestational diabetes mellitus increases the risk of developing Type 2 diabetes mellitus, a risk factor for cardiovascular disease. Factors contributing to vascular changes remain uncertain. The aim of this review was to summarize vascular structure and function changes found to occur in women with previous gestational diabetes mellitus and to identify factors that contribute to vascular dysfunction. A systematic search of electronic databases yielded 15 publications from 1998 to March 2014 that met the inclusion criteria. Our review confirmed that previous gestational diabetes mellitus contributes to vascular dysfunction, and the most consistent risk factor associated with previous gestational diabetes mellitus and vascular dysfunction was elevated body mass index. Heterogeneity existed across studies in determining the relationship of glycaemic levels and insulin resistance to vascular dysfunction.<br /> (© The Author(s) 2016.)
- Subjects :
- Adult
Biomarkers blood
Blood Glucose metabolism
Body Mass Index
Diabetes, Gestational blood
Diabetes, Gestational pathology
Diabetes, Gestational physiopathology
Diabetic Angiopathies blood
Diabetic Angiopathies pathology
Diabetic Angiopathies physiopathology
Female
Humans
Insulin blood
Insulin Resistance
Middle Aged
Obesity complications
Obesity diagnosis
Pregnancy
Risk Assessment
Risk Factors
Diabetic Angiopathies etiology
Endothelial Cells metabolism
Endothelial Cells pathology
Endothelium, Vascular metabolism
Endothelium, Vascular pathology
Endothelium, Vascular physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1752-8984
- Volume :
- 13
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Diabetes & vascular disease research
- Publication Type :
- Academic Journal
- Accession number :
- 26940821
- Full Text :
- https://doi.org/10.1177/1479164115624681