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A fatal intoxication related to MDPV and pentedrone combined with antipsychotic and antidepressant substances in Cyprus.
- Source :
-
Forensic science international [Forensic Sci Int] 2016 Aug; Vol. 265, pp. 160-5. Date of Electronic Publication: 2016 Feb 17. - Publication Year :
- 2016
-
Abstract
- This is a case report of a fatal intoxication in Cyprus related to 3,4-methylenedioxypyrovalerone (MDPV) and 2-(methylamino)-1-phenylpentan-1-one (pentedrone) intake combined with antipsychotic and antidepressant substances. A 42- year old man with a history of serious psychiatric illness was found unresponsive in his bed. Seized materials were also found close to his body. The forensic autopsy reported myocardial infarction due to multidrug intoxication. Toxicology screening in blood and urine was applied. Biological specimens were analysed by enzyme immunoassay procedure and GC/MS. MDPV, pentedrone and etizolam detected and quantitated in blood and urine. Other drugs quantitated in blood were also olanzapine, mirtazapine, and ephedrine. This was the first fatal case reported in Cyprus associated with new psychoactive substances. Additionally, this was the first case reported to Early Warning System of the European Monitoring Center of Drugs and Drug Abuse (EMCDDA), related to multidrug intoxication, attributed to the consumption of cathinones, designer benzodiazepines, and other drugs.<br /> (Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Adult
Antidepressive Agents blood
Antidepressive Agents poisoning
Antipsychotic Agents blood
Antipsychotic Agents poisoning
Benzodioxoles blood
Benzodioxoles poisoning
Cyprus
Fatal Outcome
Forensic Toxicology
Humans
Male
Methylamines blood
Methylamines poisoning
Pentanones blood
Pentanones poisoning
Poisoning blood
Pyrrolidines blood
Pyrrolidines poisoning
Synthetic Cathinone
Poisoning diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1872-6283
- Volume :
- 265
- Database :
- MEDLINE
- Journal :
- Forensic science international
- Publication Type :
- Academic Journal
- Accession number :
- 26930452
- Full Text :
- https://doi.org/10.1016/j.forsciint.2016.02.017