Back to Search
Start Over
Calcium Phosphate Cement Cranioplasty Decreases the Rate of Cerebrospinal Fluid Leak and Wound Infection Compared with Titanium Mesh Cranioplasty: Retrospective Study of 672 Patients.
- Source :
-
World neurosurgery [World Neurosurg] 2016 Nov; Vol. 95, pp. 414-418. Date of Electronic Publication: 2016 Feb 26. - Publication Year :
- 2016
-
Abstract
- Objective: A variety of biomaterials have been developed for cranial reconstruction after craniectomy, including polyethylene titanium mesh and calcium phosphate cement. This study sought to compare complication rates of calcium phosphate cement and titanium mesh cranioplasty in patients undergoing retromastoid craniectomy.<br />Methods: The authors retrospectively reviewed clinical data from 672 consecutive patients who underwent retromastoid craniectomy at a single institution for microvascular decompression or tumor resection from July 2009 to July 2014. Of these, 336 patients received calcium phosphate cement cranioplasty and 336 underwent (polyethylene) mesh cranioplasty. Charts were abstracted for occurrence of cerebrospinal fluid (CSF) leak, wound infection and/or other wound complication, and the groups were compared.<br />Results: In the mesh cranioplasty group, there were 38 complications related to the surgical site, including 18 infections (5.4%), 20 patients (6%) with CSF leak or pseudomeningocele, and no (0%) other wound complications. In the cement cranioplasty cohort, 2 patients (0.6%) experienced wound infection, no patients (0%) had CSF leak, and 2 patients (0.6%) had other wound complications (including one sterile wound dehiscence and one reoperation for removal of excess cement). There was a statistically significant decrease in the rate of wound infection and CSF leak in the patients who underwent cement cranioplasty (P <0.001 for both).<br />Conclusions: Calcium phosphate cement cranioplasty offers an alternative to titanium cranioplasty and may reduce the risk of surgical site complication. Randomized, prospective comparisons of cement cranioplasty to traditional techniques are warranted.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Brain Neoplasms surgery
Decompressive Craniectomy
Female
Glossopharyngeal Nerve Diseases surgery
Hemifacial Spasm surgery
Herpes Zoster Oticus surgery
Humans
Male
Microvascular Decompression Surgery
Middle Aged
Polyethylene
Postoperative Complications epidemiology
Retrospective Studies
Skull surgery
Trigeminal Neuralgia surgery
Young Adult
Bone Cements therapeutic use
Calcium Phosphates therapeutic use
Cerebrospinal Fluid Leak epidemiology
Plastic Surgery Procedures methods
Surgical Mesh
Surgical Wound Infection epidemiology
Titanium
Subjects
Details
- Language :
- English
- ISSN :
- 1878-8769
- Volume :
- 95
- Database :
- MEDLINE
- Journal :
- World neurosurgery
- Publication Type :
- Academic Journal
- Accession number :
- 26921704
- Full Text :
- https://doi.org/10.1016/j.wneu.2016.02.071