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[Treatment of pneumonia caused by Legionella, Mycoplasma, Chlamydiae and Rickettsia using ofloxacin].
- Source :
-
Pathologie-biologie [Pathol Biol (Paris)] 1989 Dec; Vol. 37 (10), pp. 1137-40. - Publication Year :
- 1989
-
Abstract
- To asses the efficacy and the safety of ofloxacin as therapy of pneumonia caused by intracellular pathogens, 35 patients were studied (26 male, 9 female, mean age: 52.5 +/- 16.6 years). Causative pathogens were Chlamydia psittaci (n = 13), Legionella pneumophila (n = 10), Mycoplasma pneumoniae (n = 7) and Coxiella burnetii (n = 5). Ofloxacin was administered orally in 32 cases (200 mg b.i.d. in 80% of cases) and by I.V. route in 3 cases. All patients were cured without any side effects. In conclusion, ofloxacin appears, in our study, as an efficient therapy for these pneumonias. It could be considered as a valuable alternative to other antimicrobial agents with intra-cellular activity.
- Subjects :
- Adult
Aged
Female
France epidemiology
Humans
Legionnaires' Disease epidemiology
Male
Middle Aged
Multicenter Studies as Topic
Pneumonia, Mycoplasma drug therapy
Pneumonia, Mycoplasma epidemiology
Pneumonia, Rickettsial epidemiology
Psittacosis drug therapy
Psittacosis epidemiology
Legionnaires' Disease drug therapy
Ofloxacin therapeutic use
Pneumonia, Rickettsial drug therapy
Subjects
Details
- Language :
- French
- ISSN :
- 0369-8114
- Volume :
- 37
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Pathologie-biologie
- Publication Type :
- Academic Journal
- Accession number :
- 2691969