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Diagnosis and management of typical and atypical lung carcinoids.

Authors :
Pusceddu S
Lo Russo G
Macerelli M
Proto C
Vitali M
Signorelli D
Ganzinelli M
Scanagatta P
Duranti L
Trama A
Buzzoni R
Pelosi G
Pastorino U
de Braud F
Garassino MC
Source :
Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2016 Apr; Vol. 100, pp. 167-76. Date of Electronic Publication: 2016 Feb 18.
Publication Year :
2016

Abstract

An estimated 20% to 30% of all neuroendocrine tumours originate in the bronchial tree and lungs. According to the 2015 World Health Organization categorization, these tumours are separated into four subtypes characterized by increasing biological aggressiveness: typical carcinoid, atypical carcinoid, large-cell neuroendocrine carcinoma and small-cell carcinoma. Although typical and atypical lung carcinoids account for less than 1-5% of all pulmonary malignancies, the incidence of these neoplasms has risen significantly in recent decades. Surgery is the treatment of choice for loco-regional disease but for advanced lung carcinoids there is no recognized standard of care and successful management requires a multidisciplinary approach. The aim of this review is to provide a useful guide for the clinical management of lung carcinoids.<br /> (Copyright © 2016. Published by Elsevier Ireland Ltd.)

Details

Language :
English
ISSN :
1879-0461
Volume :
100
Database :
MEDLINE
Journal :
Critical reviews in oncology/hematology
Publication Type :
Academic Journal
Accession number :
26917456
Full Text :
https://doi.org/10.1016/j.critrevonc.2016.02.009