Genotoxicity in Mice Following AAV Gene Delivery: A Safety Concern for Human Gene Therapy?

Subjects

Subjects :

Animals
Dependovirus immunology
Drug Evaluation, Preclinical
Humans
Immunity, Cellular
Immunity, Humoral
Mice
DNA Damage
Dependovirus physiology
Genetic Therapy adverse effects

Details

Language :

English

ISSN :

1525-0024

Volume :

24

Issue :

2

Database :

MEDLINE

Journal :

Molecular therapy : the journal of the American Society of Gene Therapy

Publication Type :

Academic Journal

Accession number :

26906613

Full Text :

https://doi.org/10.1038/mt.2016.17