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Total Aortic Replacement for a 9-Year-Old Boy With Loeys-Dietz Syndrome.

Authors :
Inoue Y
Minatoya K
Oda T
Itonaga T
Seike Y
Tanaka H
Sasaki H
Kobayashi J
Source :
The Annals of thoracic surgery [Ann Thorac Surg] 2016 Mar; Vol. 101 (3), pp. 1185-8.
Publication Year :
2016

Abstract

Loeys-Dietz syndrome (LDS) is a recently identified rare connective tissue disorder caused by mutations of the transforming growth factor-β receptors and first described in 2005. It is an autosomal dominant syndrome with 2 different phenotypic expressions-LDS I and II. LDS is characterized by the triad of arterial tortuosity and aneurysm, hypertelorism, and a bifid uvula or cleft palate. We present a case of a 9-year-old boy diagnosed with LDS who underwent urgent thoracoabdominal aortic aneurysm repair followed by total arch replacement and aortic valve-sparing root replacement (AVSRR).<br /> (Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1552-6259
Volume :
101
Issue :
3
Database :
MEDLINE
Journal :
The Annals of thoracic surgery
Publication Type :
Academic Journal
Accession number :
26897206
Full Text :
https://doi.org/10.1016/j.athoracsur.2015.05.071