A curious fact: Photic sneeze reflex. Autosomical dominant compelling helio-ophthalmic outburst syndrome.

Authors :: Sevillano C
Parafita-Fernández A
Rodriguez-Lopez V
Sampil M
Moraña N
Viso E
Cores FJ
Source :: Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol] 2016 Jul; Vol. 91 (7), pp. 305-9. Date of Electronic Publication: 2016 Feb 17.
Publication Year :: 2016
Abstract: Objective: To assess ocular involvement in the pathophysiology of autosomal dominant compelling helio-ophthalmic outburst syndrome (ACHOOs).<br />Methods: An interview was conducted with a Caucasian family that showed clinical features of ACHOOs. Twelve of them had photic reflex and were recruited. A complete eye evaluation was made.<br />Results: A dominant autosomal inheritance with mild penetrance was demonstrated, with 67% of the studied subjects showing some degree of prominent corneal nerves. No other eye changes were found.<br />Conclusions: Prominent corneal nerves may be associated with ACHOOs. The other eye structures studied do not seem to play a role in ACHOOs. Further studies are needed to understand the physiology of the ACHOOs.<br /> (Copyright © 2016 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.)

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